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. 2020 Aug 17;319(4):F647–F653. doi: 10.1152/ajprenal.00112.2020

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Published by the American Physiological Society

PMC Copyright notice

Fig. 5. — Effect of intramedullary (pro)renin receptor inhibition on DOCA-salt (DOCA) kidney injury in rats. Following 2-wk treatment with DOCA and PRO20, kidney weight (A) was measured, and day 14 urine was harvested and subjected to ELISA analysis of urinary albumin (B) and urinary neutrophil gelatinase-associated lipocalin (NGAL; C). n = 5 animals/group. CTR, control; IM PRO20, intramedullary PRO20 infusion; IV PRO20, intravenous PRO20 infusion. Statistical significance was determined using one-way ANOVA with the Bonferroni test for multiple comparisons, and P values are indicated. Data are means ± SE.