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Tumorsphere growth and genetic profiles of normal pleura (NP)-designated cell lines. A: phase-contrast images of NP1, NP4, and NP5 cell lines compared with H2052 malignant pleural mesothelioma cell line (known to be tumorigenic) under conditions of anchorage-independent cell growth. Tumorsphere assay results are shown. B: representative NP cell lines (NP1, NP4, NP5) were characterized by karyotype and short-tandem-repeat analyses.
