Skip to main content
. 2020 Sep 29;10(11):3929–3947. doi: 10.1534/g3.120.401723

Table 6. Human genes orthologous to yeast resistance genes.

Yeast Genea Human Geneb Description/Function
AKL1 AAK1 Adaptor protein 2 associated kinase 1
ATP11 ATPAF1 F1-ATPase assembly factor 1
ATP15 ATP5E ϵ subunit of human ATP synthase
BLM10 PSME4 Proteasome activator complex subunit 4
CKB1 CSNK2B Casein kinase II subunit beta
CKB2 CSNK2B Casein kinase II subunit beta
CLB5 CCNE2 G1/S-specific cyclin-E2
DST1 TCEA1 Transcription elongation factor A1
DPB3 CHRAC1 Chromatin accessibility complex protein 1
FKH2 FOXE1 Forkhead box protein E1
FUM1 FH Fumarate hydratase, mitochondrial
GLO1 GLO1 GLyOxalase
GRE3 AKRA1,B1,D1, E2, B10 Aldo-keto reductase family 1 member, A1, B1, D1, E2, B10
GTB1 PRKCSH Protein kinase C substrate 80K-H
HHF1 HIST1H4D Histone H4
MIS1 MTHFD1 Methylenetetrahydrofolate dehydrogenase
MIX23 CCDC58 Coiled-coil domain-containing protein 58
MMS4 EME1 and EME2 Essential meiotic structure-specific endonuclease 1, essential meiotic structure-specific endonuclease subunit 2
MRPL35 MRPL38 Large subunit mitochondrial ribosomal protein L38
NRP1 TEX13B N (asparagine)-Rich Protein, Testis-expressed protein 13B
PEX3 PEX3 Peroxisomal biogenesis factor 3
PPG1 PPP2CB Protein Phosphatase involved in Glycogen accumulation
PSY2 PPP4R3B Serine/threonine-protein phosphatase 4 regulatory subunit 3B
RAD1 ERCC4 DNA repair endonuclease XPF
RAD2 ERCC5 DNA repair protein complementing XP-G cells
RAD4 XPC DNA repair protein complementing XP-C cells
RAD5 HLTF Helicase-like transcription factor involved in DNA damage tolerance
RAD10 ERCC1 Excision Repair Cross-Complementing 1 ERCC1
RAD17 RAD1 Cell cycle checkpoint protein RAD1
RAD18 RAD18 E3 ubiquitin-protein ligase RAD18
RAD23 RAD23A UV excision repair protein RAD23 homolog A
RAD54 RAD54L DNA repair and recombination protein RAD54-like
RAD55 RAD51B DNA repair protein RAD51 paralog B
RAV1 DMXL2 Dmx like 2 also known as rabconnectin-3, involved in vacuolar acidification
REV1 REV1 REV1, DNA directed polymerase
REV3 REV3L REV3 Like, DNA directed polymerase zeta catalytic subunit
RNR3 RRM1 Ribonucleotide reductase catalytic subunit M1
ROT2 GANAB Glucosidase alpha, neutral C
RPN10 PSMD4 26S proteasome non-ATPase regulatory subunit 4
RPS4A RPS4X Ribosomal Protein of the Small subunit, 40S ribosomal protein S4, X isoform
SPO1 PLA2G4A Phospholipase A2 group IVA
SSM4 MARCH6 Membrane associated ring-CH-type finger 6
TMA20 MCTS1 Malignant T-cell-amplified sequence 1, translation re-initiation and release factor
TRM9 ALKB8 Alkylated DNA repair protein alkB homolog 8
YIH1 IMPACT Impact RWD domain protein; translational regulator that ensures constant high levels of translation upon a variety of stress conditions; impact RWD domain protein
YND1 ENTPD4 and ENTPD7 Ectonucleoside triphosphate diphosphohydrolase 4 and 7
a

For full description, see Table 1 and Table 2.