Figure 6.

Asthma tissue transcriptome linked to drug repurposing. The blue connected dots (in A) indicate overlap between sample types (gray tracks) while the asterisk showing perturbagen connecting maximum tissue types. The bar chart (B) indicates the number of unique perturbagens for each sample type with overlapped portion in orange. Clustered heatmap (C) connecting asthma-relevant tissue/ samples to perturbagens has been generated using respective connectivity S1 Table scores) in each tissue. Asthma associated up and down-regulated genes identified form different tissue/ sample types were used to identify perturbagens that can potentially reverse asthma signature in respective sample type.