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. 2020 Sep 8;10(11):4049–4062. doi: 10.1534/g3.120.401718

Table 3. Perturbagens associated with at least three asthma-relevant asthma sample types. occurrence (connection to number of asthma tissues), associated asthma tissue/ sample type and their known association with allergy/ asthma/ lung diseases (known/ unknown) have been Mentioned.

Perturbagen Occurrences Associated samples Indicated in allergy/ asthma/ lung disease
KLF6 (Kruppel like factor 6) 5 AirEpi, Macrophages, FibroDistal, CD8+, Nasal Yes
BCL10 (B-cell lymphoma/ leukemia 10) 4 Macrophages, FibroDistal, CD4+, Blood Yes
HOXB13 Homeobox protein Hox-B13 4 Macrophages, Sputum, FibroDistal, Nasal No
IFNB1(Interferon beta 1) 4 Sputum, FibroDistal, CD8+, Blood Yes
Entinostat 4 Macrophages, FibroDistal, CD8, Nasal No
ATOX1(Antioxidant 1 Copper Chaperone) 3 FibroDistal, CD4, FibroProximal No
BAMBI(BMP and activin membrane bound inhibitor) 3 Macrophages, Sputum, Blood Yes
BMS-345541 3 FibroDistal, CD8+, Nasal Yes
CCNL1 (cyclin L1) 3 Macrophages, FibroDistal, CD8+ No
CDCA8 (cell division cycle associated 8) 3 AirEpi, CD8+, Blood No
DHX8 (DEAH-box helicase 8) 3 Sputum, Bronchial, Blood Yes
DTX2 (deltex E3 ubiquitin ligase) 3 AirEpi, Sputum, Nasal No
KLF3 (Kruppel like factor 3) 3 Bronchial, FibroDistal, CD8+ Yes
LASP1 (LIM and SH3 protein 1) 3 AirEpi, Macrophages, CD8+ Yes
LOXL1 (lysyl oxidase like 1) 3 AirEpi, Sputum, Blood Yes
PPP2R3C (protein phosphatase 2 regulatory subunit B’’gamma) 3 AirEpi, Macrophages, Blood Yes
PREB(prolactin regulatory element binding) 3 Macrophages, FibroDistal, FibroProximal No
PUF60 (poly-U binding splicing factor 60) 3 Macrophages, CD8+, Nasal No
SORBS3 (sorbin and SH3 domain containing 3) 3 Macrophages, FibroProximal, Nasal No
TRIP10 (Thyroid Hormone Receptor Interactor 10) 3 Macrophages, Bronchial, FibroDistal No
XPO7 (Exportin 7) 3 AirEpi, Sputum, Bronchial Yes
YWHAZ 3 AirEpi, Bronchial, Nasal No
Calyculin 3 Macrophages, FibroDistal, Blood No