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. 2020 Oct 22;11:569206. doi: 10.3389/fpsyg.2020.569206

TABLE 2.

Three Meta-Analyses About Exercise Intervention as Treatment for Depression.

Study Time Period Searched Databases Number of Studies Sample (s) Age Design Interventions Outcome Measures Meta-Analysis of Outcomes Results
Schuch et al., 2016a 2013.01– 2015.08 ASP, MEDLINE, Psychology, BSC, PsycINFO, SPORTDiscus, CINAHL Plus, PubMed 25 1,487 18.4 to 76.4 (mean) RCTs Aerobic, resistance, mixed exercises BDI, CSDD, GDS, HAMD, MADRS, MMPI, PHQ-9, SCL SMD, 95% CI Exercise has a large and significant antidepressant effect in people with depression.
Kvam et al., 2016 2007.01– 2014.11 SD, PsycINFO, MEDLINE, EMBASE, CENTRAL 23 977 18 to 69 (mean) RCTs Aerobic exercise, aerobic exercise + pharmacotherapy BDI, CESD, HAMD, SCL-90 Hedges’s, 95% CI Physical exercise is an effective intervention for depression.
Cooney et al., 2013 All years–2013.03 Cochrane Library, CENTRAL, MEDLINE, EMBASE, PsycINFO, SD 39 2,326 > 18 RCTs Aerobic, resistance, aerobic+ resistance BDI, HAMD SMD, 95% CI Exercise may be moderately more effective than no therapy for reducing symptoms of depression, but more evidence is needed.

ASP, Academic Search Premier; BDI, Beck Depression Inventory; BSC, Behavioral Sciences Collection; CENTRAL, Cochrane Central Register of Controlled Trials; CESD, Center for Epidemiologic Studies Depression Scale; CSDD, Cornel Scale for Depression in Dementia; GDS, Geriatric Depression Scale; HAMD, Hamilton Rating Scale for Depression; MADRS, Montgomery–Asberg Depression Rating Scale; MMPI, Minnesota Multiphasic Personality Inventory; PHQ-9, Patient Health Questionnaire; SD, Sports Discus; SMD, standardized mean difference; SCL and SCL-90, Symptom Checklist; 95% CI, 95% confidence interval.