Figure 6.

SNHG1 binding EZH2 activates PI3K/AKT/mTOR and Wnt/β-catenin signaling pathways in LNCap and PC-3 cells. (A) Western blot was used to detect the protein expression levels of PI3K/AKT/mTOR signaling pathway-related proteins p-PI3K, p-AKT, p-mTOR and p-p70S6K in LNCaP and PC3 cells transfected with NC, si-SNHG1, si-EZH2, si-SNHG1+con, si-SNHG1+EZH2. (B) Western blot was used to detect the expression levels of Wnt/β-catenin signaling pathway related proteins Wnt1, β-catenin, c-myc and Cyclin D1 in LNCaP and PC3 cells transfected with NC, si-SNHG1, si-EZH2, si-SNHG1+con and si-SNHG1+EZH2.