Table 3.

Comparison of the prognostic accuracies of the nomogram and the 8^th AJCC-TNM.

		Nomogram	AJCC 8th TNM	p-value
Training cohort
RFS	C-index (95% CI)	0.774 (0.753–0.794)	0.707 (0.685–0.729)	<0.001
	AIC	6,201.097	6,419.61	–
OS	C-index (95% CI)	0.766 (0.747–0.785)	0.700 (0.680–0.620)	<0.001
	AIC	7,377.636	7,623.727	–
Internal validation cohort
RFS	C-index (95% CI)	0.770 (0.730–0.810)	0.732 (0.693–0.770)	0.013
	AIC	1,249.137	1,267.904	–
OS	C-index (95% CI)	0.781 (0.742–0.821)	0.735 (0.696–0.775)	<0.001
	AIC	1,209.733	1,236.066	–
External validation cohort
RFS	C-index (95% CI)	0.686 (0.609–0.763)	0.596 (0.510–0.684)	<0.001
	AIC	388.265	402.46	–
OS	C-index (95% CI)	0.692 (0.627–0.757)	0.593 (0.528–0.658)	<0.001
	AIC	604.176	627.198	–

Statistics are for 5-year RFS and OS rates. C-index, Harrell concordance index; AIC, Akaike Information Criterion.