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Comparison of prostate cancer (PCa) polygenic risk between PCa cases and controls. (A) Distribution of the polygenic risk score (PRS) in PCa cases and controls (black solid line represents cutoff value at the maximum J). (B) Distribution of the PRS in PCa cases and controls (each dashed line represents high-risk PRS group—top 2.5, 5, 10, and 20%). (C) Distribution of cases and controls according to PRS quantiles. (D) Odds ratio for developing PCa according to PRS quantiles.
