TABLE 3.
Candidate PCa-associated SNPs retained after LD clumping for construction of PRS (n = 6).
SNP | CHR | BP | Gene | P | SNPs in LD | Risk allele | Minor allele = risk allele | Weight [log(OR)] |
rs1016343 | 8 | 128103937 | PRNCR1 | 1.46 × 10–15 | rs13252298, rs16901979 | A | Y | 0.469 |
rs4242384 | 8 | 128518554 | CASC8;LOC105375754 | 1.97 × 10–10 | rs1447295, rs4242382, rs7837688 | C | Y | 0.444 |
rs7501939 | 17 | 36101156 | HNF1B | 6.42 × 10–7 | rs4430796 | C | N | 0.333 |
rs1512268 | 8 | 23526463 | NKX3.1;LOC107986930 | 6.51 × 10–6 | – | A | Y | 0.265 |
rs2735839 | 19 | 51364623 | KLK2;KLK3 | 6.84 × 10–6 | – | G | N | 0.266 |
rs2016588 | 6 | 159425707 | LOC105378083 | 1.69 × 10–5 | – | A | Y | 0.237 |