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Autophagy vesicles in cancer cells sensitive and resistant to chemotherapy. TEM images showing the presence of autophagy vesicles in JHU029 cell lines derived from laryngeal cancer, sensitive, and resistant (R) to cisplatin (see arrows). As was demonstrated by our group (187), cancer cells resistant to chemotherapy generate more autophagy vesicles than sensitive ones, which is correlated with the resistant phenotype developed.
