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. 2020 Nov 4;156(12):1–9. doi: 10.1001/jamadermatol.2020.3111

Table 2. Multivariate Incidence Rate Ratios (IRRs) for Sebaceous Carcinoma Risk Among US Solid Organ Transplant Recipients.

Characteristic Observed cases Incidence rate per 100 000 person-years Multivariate IRR (95% CI)a P value
Sex
Female 19 2.81 [Reference] <.001
Male 83 7.90 2.46 (1.48-4.07)
Race/ethnicity
Non-Hispanic .03
White 80 7.15 [Reference]
Black 4 1.46 0.28 (0.10-0.77)
Hispanic 13 5.35 1.09 (0.60-1.98)
Asian or Pacific Islander 5 5.44 1.01 (0.40-2.51)
Age at transplant, y
0-44 13 1.80 [Reference] <.001b
45-54 31 6.77 3.59 (1.87-6.90)
55-64 37 9.22 4.73 (2.47-9.05)
≥65 21 14.5 7.85 (3.85-16.0)
Transplanted organ
Kidney 59 5.87 [Reference] .09
Liver 13 3.43 0.52 (0.28-0.98)
Heart 18 9.58 0.89 (0.51-1.56)
Lung 8 13.3 1.87 (0.87-4.03)
Other or multiple 4 4.21 0.92 (0.33-2.57)
Induction therapy with thymoglobulin
No 73 5.30 [Reference] .009
Yes 29 8.29 1.82 (1.16-2.86)
Posttransplant diagnosis of cutaneous squamous cell carcinoma
No 83 4.89 [Reference] <.001
Yes 19 65.6 4.60 (2.67-7.94)
Time since transplant, y
0-1.9 10 1.88 [Reference] <.001b
2-4.9 30 5.47 2.86 (1.39-5.85)
5-9.9 35 7.62 4.04 (1.98-8.23)
≥10 27 14.4 8.40 (3.94-17.90)
a

Multivariate model adjusted for variables listed in the table.

b

P value for trend.