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. 2020 Nov 4;10:19042. doi: 10.1038/s41598-020-76154-7

Table 2.

Bruch’s membrane opening-minimum rim width and retinal nerve fiber layer of the included subjects.

Characteristics Values p value
GS (n = 229) Early NTG (n = 168)
BMO-MRW
BMO-fovea angle° − 5.43 ± 3.19 − 5.70 ± 3.19 .097
BMO area (mm2) 2.45 ± 0.53 2.30 ± 0.55 .020
BMO-MRW G (um) 263.30 ± 41.57 206.77 ± 43.96 < .001
BMO-MRW T 192.97 ± 41.16 159.54 ± 38.02 < .001
BMO-MRW TS 267.89 ± 43.06 206.40 ± 60.51 < .001
BMO-MRW TI 295.75 ± 53.04 196.31 ± 65.92 < .001
BMO-MRW N 275.96 ± 55.72 228.40 ± 58.06 < .001
BMO-MRW NS 291.02 ± 57.55 234.69 ± 62.61 < .001
BMO-MRW NI 321.98 ± 54.94 236.53 ± 63.80 < .001
RNFL thickness
RFNL G (µm) 102.10 ± 10.05 82.71 ± 13.14 < .001
RFNL T 78.63 ± 12.24 66.51 ± 13.17 < .001
RFNL TS 142.62 ± 21.31 112.09 ± 29.72 < .001
RFNL TI 156.01 ± 19.66 101.73 ± 35.21 < .001
RFNL N 77.58 ± 15.63 68.21 ± 14.57 < .001
RFNL NS 114.78 ± 25.65 100.83 ± 27.29 < .001
RFNL NI 113.61 ± 23.78 91.91 ± 20.14 < .001
RFNL classification (WNL/BL/ONL)
RFNL G (µm) WNL (94.3%), BL (4.4%), ONL (1.3%) WNL (38.7%), BL (20.2%), ONL (41.4%) < .001
RFNL T WNL (97.8%), BL (1.7%), ONL (0.4%) WNL (85.1%), BL (7.1%), ONL (7.7%) .049
RFNL TS WNL (95.6%), BL (2.6%), ONL (1.7%) WNL (63.7%), BL (15.5%), ONL (20.8%) < .001
RFNL TI WNL (93.4%), BL (5.7%), ONL (0.9%) WNL (33.9%), BL (7.7%), ONL (58.3%) < .001
RFNL N WNL (86.9%), BL (8.7%), ONL (4.4%) WNL (70.8%), BL (15.5%), ONL (13.7%) < .001
RFNL NS WNL (94.3%), BL (3.5%), ONL (2.2%) WNL (76.2%), BL (15.5%), ONL (8.3%) < .001
RFNL NI WNL (90.0%), BL (8.3%), ONL (1.7%) WNL (77.4%), BL (15.5%), ONL (7.1%) .002

BMO-MRW, Bruch’s membrane opening-minimum rim width. RNFL, retinal nerve fiber layer: G, global. T, temporal. TS, superotemporal. NS, superonasal. N, nasal. NI, inferonasal. TI, inferotemporal. Statistical analysis between GS and early NTG for BMO-MRW and RNFL thickness was done by Wilcoxon signed-rank test, Bold font indicates significant p values (p < 0.05); RNFL classification: WNL, within normal limits. BL, borderline. ONL, outside normal limits. Statistical analysis between GS and early NTG was done by Mann–Whitney U Test for RNFL classification. Bold font indicates significant p values (p < 0.05).