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. 2020 Nov 4;10:18972. doi: 10.1038/s41598-020-75987-6

Table 2.

Characteristics of patients with suspected carbohydrate malabsorption and overview of test results.

Patients All 2–5 years 6–8 years 9–11 years 12–14 years 15–18 years
Tests, n (%)
Fructose 187 (100) 27 (14) 35 (19) 47 (25) 35 (19) 43 (23)
Lactose 82 (100) 20 (24) 13 (16) 17 (21) 14 (17) 18 (22)
Sex, female/male ratio
Fructose 1.9 2.0 1.5 1.8 0.8 3.3
Lactose 1.8 1.5 0.6 2.4 1.8 2.6
Age, years (range/mean)
Fructose 2.3–18 (11.0) 4.5 7.7 10.4 13.3 16.4
Lactose 2.9–18 (10.4) 4.5 7.1 10.7 13.6 16.5
HBT positive, n (%)
Fructose 113 (60) 23 (12) 24 (13) 32 (17) 20 (11) 14 (7)
Lactose 16 (20) 3 (4) 3 (4) 2 (2) 3 (4) 5 (6)
MBT positive, n (%)
Fructose 66 (35) 16 (9) 19 (10) 20 (11) 7 (4) 4 (2)
Lactose 14 (17) 2 (2) 3 (4) 2 (2) 4 (5) 3 (4)
BST positive, n (%)
Fructose 109 (58) 13 (7) 18 (10) 27 (14) 17 (9) 34 (18)
Lactose 12 (15) 0 (0) 1 (1) 3 (4) 3 (4) 5 (6)
Symptoms positive, n (%)
Fructose 51 (27) 11 (6) 5 (3) 13 (7) 6 (3) 16 (9)
Lactose 23 (28) 2 (2) 2 (2) 7 (9) 4 (5) 8 (10)
NMP positive, n (%)
Fructose 47 (25) 7 (4) 5 (3) 12 (6) 13 (7) 10 (5)
Lactose 3 (4) 1 (1) 0 (0) 0 (0) 0 (0) 2 (2)

HBT hydrogen breath test (an increase of H2 ≥ 20 ppm over baseline was considered positive). MBT methane breath test (a CH4 concentration ≥ 10 ppm at any time point was considered positive). BST Blood sugar test (an increase of blood glucose < 1.1 mmol/L at any time point was considered positive). Symptoms patients who showed or reported any symptoms during the test procedure. NMP non-methane producer (patients with a positive HBT but with a negative MBT).