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. 2020 Nov 4;10:19027. doi: 10.1038/s41598-020-75835-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Menu for creating grayscale elements and example of output. (A) The menu for creating grayscale elements allows the user to select a specific color for each input image channel. The output channel is assigned with the drop down menu labeled “Output image channel”. Macro commands are added with the “Add macro commands” button. Clicking “Preview” displays a temporary preview of the grayscale element using the selected settings. (B) An example of a grayscale element output obtained by applying the settings shown in (A).