Table 1. Comparison of Different Extraction Methods of FA.
| method | principle | equipment | time | advantages | disadvantages |
|---|---|---|---|---|---|
| alkali-soluble acid precipitation23,24 | solubility differences | conventional extractor | 5–6 h | easy to operate | time-consuming |
| low extraction yield | |||||
| high content of impurities | |||||
| chemical degradation25,26 | oxidation increases acid solubility | conventional extractor | 36–72 h | high yielding | time-consuming |
| expensive | |||||
| ultrasound-assisted27 | ultrasound energy | ultrasonic water bath | 1 h | rapid | lower efficiency than the microwave method |
| range of ultrasonic action is narrow | |||||
| microwave-assisted28 | microwave energy | microwave extractor | 10–20 min | very rapid | difficult to industrialize |