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. 2020 Nov 4;11:5581. doi: 10.1038/s41467-020-19319-2

Table 1.

Cell-specific transcripts identified from open chromatin.

Cell type Protein coding lncRNA microRNA
Neuronal 4075 3417 87
Glutamatergic 807 1123 8
GABAergic 834 698 12
non-Neuronal 6289 4485 89
Oligodendrocyte 2318 1386 25
Microglia/astrocytes 1887 1957 33

To infer the transcriptome from chromatin accessibility, genes were linked to cell-specific open chromatin regions by direct overlap of the TSS. “Neuronal” is not simply the sum of “Glutamatergic” and “GABAergic”, as the latter two exclude chromatin that are not specific to either neuronal subtype (Methods). Likewise, “non-Neuronal” is not the sum of the two constituent cell subtypes. For microRNA host genes, only genes encoding one or more conserved microRNA were considered.