Table 1. Biochemical Parameters in Wistar Ratsa.
fructose-naïve |
fructose-fed |
||||||
---|---|---|---|---|---|---|---|
control | walnuts | fructose | fructose + walnuts | Fa | Wb | FxWc | |
glucose (mmol/L) | 5.21 ± 0.14 | 5.20 ± 0.13 | 5.54 ± 0.19 | 5.30 ± 0.14 | 0.162 | 0.405 | 0.447 |
ALT (U/L) | 50.81 ± 2.88 | 51.37 ± 3.0 | 46.74 ± 4.99 | 43.87 ± 2.49 | 0.106 | 0.741 | 0.625 |
AST (U/L) | 115.80 ± 7.72 | 120.34 ± 8.52 | 128.47 ± 16.7 | 93.86 ± 4.57 | 0.511 | 0.158 | 0.069 |
TAG (mmol/L) | 0.85 ± 0.06 | 0.96 ± 0.09 | 1.02 ± 0.09 | 1.33 ± 0.17 | 0.019 | 0.060 | 0.349 |
uric acid (μmol/L) | 28.72 ± 1.90 | 28.42 ± 1.03 | 31.42 ± 2.91 | 24.59 ± 1.40 | 0.773 | 0.076 | 0.103 |
creatinine (μmol/L) | 29.70 ± 0.87 | 31.34 ± 0.88 | 27.14 ± 0.85 | 26.52 ± 0.86 | <0.001 | 0.559 | 0.199 |
TC (mmol/L) | 2.29 ± 0.10 | 2.02 ± 0.11 | 2.55 ± 0.18 | 2.33 ± 0.08 | 0.031 | 0.056 | 0.821 |
LDL-c (mmol/L) | 0.39 ± 0.04 | 0.31 ± 0.03 | 0.45 ± 0.06 | 0.42 ± 0.04 | 0.050 | 0.230 | 0.576 |
HDL-c (mmol/L) | 1.91 ± 0.07 | 1.69 ± 0.09 | 2.17 ± 0.14 | 1.91 ± 0.08 | 0.020 | 0.019 | 0.821 |
TC/HDL-c | 1.20 ± 0.02 | 1.19 ± 0.02 | 1.17 ± 0.01 | 1.23 ± 0.02 | 0.930 | 0.196 | 0.104 |
LDL-c/HDL-c | 0.20 ± 0.01 | 0.18 ± 0.02 | 0.20 ± 0.01 | 0.22 ± 0.01 | 0.219 | 0.910 | 0.279 |
Data are presented as mean ± SEM, n = 9. a,b,cProbabilities upon two-way ANOVA for fructose effect (F), walnut effect (W), and interaction between fructose and walnuts (FxW), respectively, upon 6 weeks. ALT, alanine aminotransferase; AST, aspartate aminotransferase; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TAG, triglycerides; TC, total cholesterol.