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. 2020 Oct 27;12(10):792–806. doi: 10.4254/wjh.v12.i10.792

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Relationship between the rs738409 genotype and the histological parameters. A: Prevalence of nonalcoholic steatohepatitis (NASH) P = 0.001; B: Prevalence of absent (S = 0) and mild (S = 1) steatosis or moderate (S = 2) and severe (S = 3) steatosis (P = 0.099); C: Prevalence of mild (A ≤ 2) or significant (A > 2) activity of NASH (P = 0.013); D: Prevalence of mild (A ≤ 2 and F ≤ 2) or significant (A > 2 and/or F > 2) grade of NASH based on the Steatosis, Activity, and Fibrosis score evaluation (P = 0.003); E: Prevalence of mild to moderate fibrosis (F0-F2) or advanced fibrosis (F3-F4) (P = 0.001); and F: Prevalence of fibrosis occurrence (P = 0.010). NASH: Nonalcoholic steatohepatitis.