Table 1.
Clinical and demographic characteristics of nonalcoholic fatty liver disease patients and controls
|
Variables
|
NAFLD, n = 148
|
Controls, n = 137
|
P
value
|
| Female | 111 (75.0%) | 97 (70.8%) | 0.426 |
| Age (yr) | 57 (46.3-63) | 55 (43 61.5) | 0.610 |
| BMI (kg/m2) | 32.8 ± 4.8 | 25.4 ± 3.3 | < 0.0001 |
| Hypertension | 98 (66.2%) | 24 (17.5%) | < 0.0001 |
| Diabetes mellitus | 69 (46.6%) | 12 (8.8%) | < 0.0001 |
| Dyslipidemia | 108 (73.0%) | 19 (13.5%) | < 0.0001 |
| Fasting glucose (mg/dL) | 101 (90-124.8) | 88 (83-98) | < 0.0001 |
| AST (U/L) | 34 (25.5-56.5) | 24 (20.3-29) | < 0.0001 |
| ALT (U/L) | 38 (28-70.5) | 29.5 (23-38) | < 0.0001 |
| GGT (U/L) | 53 (29-116) | 28 (18.5-55.5) | < 0.0001 |
| ALP (U/L) | 97 (74-116.8) | 75 (58.3-83.8) | < 0.0001 |
| Total bilirubin (mg/dL) | 0.6 (0.5-0.9) | 0.7 (0.5-0.8) | 0.438 |
| Triglycerides (mg/dL) | 162.5 (110-205.3) | 126.5 (93-176) | 0.006 |
| Total cholesterol (mg/dL) | 195.8 ± 41.5 | 179.9 ± 47.1 | 0.006 |
| VLDL (mg/dL) | 32 (22-42.3) | 24.5 (17.3-33.8) | 0.001 |
| HDL (mg/dL) | 48 (39.5-54) | 47 (40.5-60.8) | 0.404 |
| LDL (mg/dL) | 107.5 (89.5-137.9) | 96 (67.8-117.5) | 0.009 |
| Platelets (109/L) | 219.4 ± 81.8 | 254.6 ± 82.4 | 0.439 |
| Ferritin (ng/mL) | 89 (42.7-168.5) | 32 (32-32) | 0.349 |
| D vitamin (ng/mL) | 22 (19-27.7) | 26.95 (20.5-32.5) | 0.139 |
The data are expressed as n (%), or as mean ± SD for normally distributed variables and as median (interquartile range) when distribution of the variable was skewed. NAFLD: Nonalcoholic fatty liver disease; BMI: Body mass index; AST: Serum aspartate aminotransferase; VLDL: Very low-density lipoprotein; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; LDL: Low-density lipoprotein cholesterol.