Table 5.
Association of the PNPLA3 rs738409 genotype and activity of nonalcoholic steatohepatitis and fibrosis, adjusted for age, gender, body mass index and diabetes, evaluated by multivariate binary logistic regression analysis
Genotypes
|
OR
|
95%CI
|
P
value
|
Activity of NASH (A > 2 vs A < 2) | |||
CC vs CG/GG | 0.65 | 0.22-1.88 | 0.433 |
CC vs GG | 17.11 | 1.87 - 156.25 | 0.012 |
Fibrosis (presence vs absence) | |||
CC vs CG/GG | 3.05 | 1.01-9.17 | 0.046 |
CC vs GG | 7.42 | 1.55-35.47 | 0.012 |
NASH: Nonalcoholic steatohepatitis.