Table 3.
Univariate and multivariate analysis of factors associated with mortality
|
Variable
|
Univariate analysis; OR (95%CI)
|
P
value
|
Multivariate analysis1; OR (95%CI)
|
P
value
|
| Age | 1.03 (1.01-1.06) | 0.004 | 1.03 (1.00-1.06) | 0.002 |
| Child-Pugh score | 1.13 (1.04-1.23) | 0.002 | 1.09 (0.98-1.20) | 0.09 |
| MELD score | 1.06 (1.03-1.09) | < 0.001 | ||
| Presence if malnutrition2 | 1.82 (1.12-2.94) | 0.01 | ||
| Creatinine (mg/dL) | 1.94 (1.46-2.57) | < 0.001 | 2.13 (1.31-3.45) | 0.03 |
| INR | 1.60 (1.05-2.43) | 0.02 | ||
| Albumin (g/L) | 0.45 (0.29-0.68) | 0.01 | ||
| Cholesterol (mg/dL) | 0.99 (0.98-0.99) | 0.02 | ||
| Serum sodium (mEq/L) | 0.94 (0.90-0.98) | 0.003 | ||
| Protein intake 1.2-1.5 g/kg/d3 | 0.51 (0.28-0.90) | 0.02 | 0.40 (0.20-0.77) | 0.007 |
1
In order to avoid collinearity between repeating variables, in model were included: Age, Child-Pugh score, presence of malnutrition, creatinine, cholesterol, serum sodium and protein intake.
2
According to Subjective Global Assessment criteria.
3
Adherence to protein intake recommendation was analysed. INR: International normalized ratio; MELD: Model for End-Stage Liver Disease.