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. Author manuscript; available in PMC: 2020 Nov 5.
Published in final edited form as: Front Neuroendocrinol. 2019 Dec 19;56:100819. doi: 10.1016/j.yfrne.2019.100819

Figure 2. Hypothalamic Pituitary Adrenal Axis and Biological Rhythms interact to modulate neural, behavioral and physiologicla responses to stress.

Figure 2.

Normally functioning HPA responses and biological rhythms promote balance in the neurobehavioral and physiological responses to stress (A). If HPA responses (B) or biological rhythms (C) are disrupted, then the balance can shift form resilience and healthy responses to vulnerability and pathological responses.