Table 1.
Clinical characteristics of the juvenile idiopathic arthritis (JIA) cohort and control group
| Characteristics | Juvenile idiopathic arthritis | Control | ||||
|---|---|---|---|---|---|---|
| Total no. assessed | Values | Total no. assessed | Values | |||
| Female sex | 96 | 68 | (71) | 109 | 77 | (71) |
| Fulltime school or work | 94 | 73 | (78) | 109 | 86 | (79) |
| Age at visit, years, median (IQR) | 96 | 22.7 | (18.7–26.2) | 109 | 23.5 | (20.2–26.7) |
| Age at disease onset, years, median (IQR) | 96 | 6.4 | (2.7–11.7) | – | – | |
| Disease duration at visit, years, median (IQR) | 96 | 16.1 | (14.2–17.1) | – | – | |
| Oligoarticular JIA at onset | 96 | 51 | (53) | – | – | |
| Oligoarticular JIA at visita | 96 | 45 | (47) | – | – | |
| Not in remission at visitb | 96 | 53 | (55) | – | – | |
| DMARDs and/or biologics at visit | 96 | 34 | (35) | – | – | |
| HAQ, median (IQR) | 96 | 0 | (0.0–0.125) | – | – | |
| Women: hormonal contraceptives | 68 | 42 | (62) | 74 | 48 | (65) |
| Women: days since LMP, median (IQR) | 54 | 14 | (6–26) | 69 | 19 | (9–39) |
| Alcohol consumption at day of visitc | 95 | 0 | (0) | 109 | 2 | (2) |
| Use of tobacco at day of visitc | 93 | 21 | (23) | 106 | 22 | (21) |
| Consumption of coffee/tea/cola at day of visitc | 95 | 36 | (38) | 109 | 28 | (26) |
| Pain or psychotropic medication at day of visitd | 95 | 4 | (4) | 107 | 2 | (2) |
| SF-36 PCS, mean (± SD) | 96 | 51.1 | (± 9.5) | 109 | 55.1 | (± 7.9) |
| SF-36 MCS, mean (± SD) | 96 | 47.7 | (± 11.6) | 109 | 47.5 | (± 9.7) |
Unless otherwise stated, values indicate numbers (%); no. numbers; IQR interquartile range, 1st–3rd; DMARDs disease-modifying anti-rheumatic drugs; biologics biologic drugs; HAQ Health Assessment Questionnaire, 0–3 (0 = lowest, 3 = highest); LMP last menstrual period; SD standard deviation; SF-36 Short-form 36 Health Status Questionnaire, 0–100 (< 40 poor health); PCS physical component summary; MCS mental component summary
aPersistent (no. = 27) and extended (no. = 18) oligoarticular disease
bNot in remission off medication for ≥ 12 months according to the definition by Wallace et al.
cConsumption after 00.00 on the day of visit
dPain or psychotropic medication after 00.00 on the day of visit, including JIA: ibuprofen (n = 1), methylphenidate (n = 2), and prednisolone (n = 1) and control: paracetamol (n = 1) and lisdexamfetamine (n = 1)