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Multivariate analysis of hazard ratio of OS with trastuzumab discontinuation
| Variable | Adjusted Hazard Ratio | Std. Err. | 95% CI | P-value |
|---|---|---|---|---|
| Discontinuation Trastuzumab | 4.76 | 1.59 | 2.47–9.16 | < 0.001 |
| Age | 0.99 | 0.01 | 0.97–1.01 | 0.302 |
| Stage, 1 or 2 vs Stage 3 | 2.45 | 0.74 | 1.36–4.41 | 0.003 |
| Grade, 1 or 2 vs Grade 3 | 1.69 | 0.53 | 0.91–3.14 | 0.094 |
| ER status, Negative vs Positive | 0.64 | 0.20 | 0.34–1.20 | 0.163 |
| Cardiomyopathy Yes vs No | 0.31 | 0.13 | 0.14–0.70 | 0.004 |
