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. 2020 Nov 4;40(45):8683–8697. doi: 10.1523/JNEUROSCI.1006-20.2020

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Figure 2. — Selective stimulation of RTN or C1 neurons activates breathing to a comparable degree. A, Changes in f_R produced by photostimulation of RTN or C1 neurons. Two-way ANOVA for repeated measures: interaction between cell type and stimulation, F_(1,12) = 0.093, p = 0.764; effect of cell type, F_(1,12) =1.40, p = 0.258; effect of stimulation, F_(1,12) = 216.9, p < 0.0001. B, Change in V_T produced by stimulation of RTN or C1 neurons. Two-way ANOVA for repeated measures: interaction between cell type and stimulation, F_(1,12) = 0.18, p = 0.6754; effect of cell type, F_(1,12) = 0.086, p = 0.7732; effect of stimulation, F_(1,12) = 40.54, p < 0.0001. C, Changes in V_E produced by stimulation of RTN or C1 neurons. Two-way ANOVA for repeated measures: interaction between cell type and stimulation, F_(1,3) = 0.093, p = 0.7799; effect of cell type, F_(1,7) = 0.052, p = 0.8252; effect of stimulation, F_(1,7) = 63.33, p < 0.0001. D, Correlation between number of RTN neurons (Nmb+ChR2-mCherry) and changes in V_E produced by photostimulation. E, Correlation between number of C1 neurons (Th+ChR2-mCherry) and changes in V_E produced by photostimulation. *p < 0.05 (Bonferroni's multiple comparisons).