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. 2020 Nov 4;40(45):8683–8697. doi: 10.1523/JNEUROSCI.1006-20.2020

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Figure 7. — Respiratory changes during incrementing-decrementing stimulation of RTN (n = 8) or C1 (n = 6). A, Respiratory flow during RTN or C1 stimulation. This pattern of stimulation produces a smooth increase in the respiratory variables mimicking the pattern of breathing during acute CO₂ or hypoxia exposure (Souza et al., 2019). B, Average values from f_R incrementing-decrementing stimulation. Two-way ANOVA for repeated measures: interaction between cell type and time, F_(14,168) = 1.07, p = 0.3866; effect of time, F_(2.85,34.3) = 56.6, p < 0.0001; effect of cell type, F_(1,12) = 1.54, p = 0.2337. C, V_T. Two-way ANOVA for repeated measures: interaction between cell type and time, F_(14,168) = 0.70, p = 0.7671; effect of time, F_(2.3,27.9) = 23.3, p < 0.0001; effect of cell type, F_(1,12) = 0.43, p = 0.5236. D, V_E. Two-way ANOVA for repeated measures: interaction between cell type and time, F_(14,168) = 0.68, p = 0.7825; effect of time, F_(1.3,15.6) = 52.7, p < 0.0001; effect of cell type, F_(1,12) = 0.008, p = 0.9266.