Fig. 6.

Significantly differential targeting TFs in astrocytes (left) and cardiac muscle cells (right). Each row represents one TF and each column represents one network. In each plot, 100 randomly generated female-specific networks were placed on the left half and 100 randomly generated male-specific networks were placed on the right without clustering. Relative out-degree values were obtained by subtracting median summed edge weight of each TF in all 200 networks of astrocytes/cardiac muscle cells from each individual summed edge weight. Rows were hierarchically clustered with distance measured by Pearson correlation. Bars mark TFs that were significantly more active in either females (red) or males (blue)