Fig. 6.

Lineage-specific amino acid substitutions in positively selected genes at ancestral branch: (A) KAT6A, (B) LEFTY2, (C) RIF1, and (D) TCF3. Positively selected lineages and their specific amino acid substitutions are mapped on the coded protein with the arrangements of functionally important regions. The functional region represented with bar is a region of interest that cannot be described in other subsections according to UniPort. Colored boxes represent major taxonomic groups [Eutheria {purple}, Chiroptera {yellow}, and Primates/flying lemur {lime}].