Table 2.

Independent risk factors of venous thromboembolism.

			Univariate		Multivariable
	No.	2-yr (%)	HR (95%CI)	P-Value	HR (95%CI)	P-Value
Age (per unit)	798		1.02 (1.00–1.04)	0.035
Stage				<0.001
Early stage	290	4.1%	1		1
Local advanced	444	13.4%	3.11 (1.80–5.39)		2.46 (1.37–4.43)	0.004
Distant metastasis	58	44.8%	12.8 (6.29–26.0)		4.13 (1.60–10.7)	0.003
Laboratory results
WBC (per unit)	798		1.09 (1.04–1.15)	0.001
Platelet (per unit)	798		1.00 (1.00–1.01)	<0.001
Hemoglobin (per unit)	798		0.87 (0.80–0.94)	0.022
Albumin (per unit)	798		0.41 (0.28–0.58)	<0.001	0.59 (0.40–0.85)	0.005
Primary hysterectomy				<0.001
No	576	14.6%	1
Yes	222	4.0%	0.28 (0.15–0.50)
WPRT				0.015
No	316	8.2%	1
Yes	482	12.7%	1.79 (1.11–2.88)
Systemic chemotherapy				<0.001
No	718	8.5%	1		1
Yes	80	37.0%	4.74 (3.00–7.47)		2.46 (1.30–4.66)	0.006

Log-rank test for univariable analysis (among all covariates tested in Table 1, only significant covariates are listed). A Cox proportional hazard regression model for multivariable analysis (conditional backward method). Significant P-values are emboldened. Abbreviations: HR, Hazard ratio; 95%CI, 95% confidence interval; 2-yr (%), 2-year cumulative proportion; and WPRT, whole pelvic radiation therapy.