TABLE 1.
Demographics of patients with rhabdomyosarcoma and bone marrow metastasis at diagnosis (N = 27)
| N | Percentage | |
|---|---|---|
| Gender | ||
| Female | 14 | 52 |
| Male | 13 | 48 |
| Age | ||
| Age <10 years | 6 | 22 |
| Age ≥10 years | 21 | 78 |
| Subtype | ||
| Alveolar | 25 | 93 |
| PAX3-FOXO1 fusion | 22 | |
| PAX7-FOXO1 fusion | 1 | |
| Negative for FOXO1 fusion | 1 | |
| Unknown fusion status | 1 | |
| Embryonal | 2 | 7 |
| Primary site of disease | ||
| Extremity/gluteal | 14 | 52 |
| Trunk/mediastinum/paravertebral | 4 | 15 |
| Abdomen/retroperitoneum | 2 | 7 |
| Genitourinary (vulvar/paratesticular) | 2 | 7 |
| Parameningeal | 2 | 7 |
| Perineal/pelvis | 2 | 7 |
| Prostate | 1 | 4 |
| Metastatic sites | ||
| Bone marrow + bone | 2 | 7 |
| Bone marrow + lymph node | 2 | 7 |
| ≥3 sites including bone marrow | 23 | 85 |
| Oberlin score | ||
| 2 | 2 | 7 |
| 3 | 11 | 41 |
| 4 | 14 | 52 |
Note: Alveolar fusion status indicates fusion presence in bone marrow and/or tumor at diagnosis. The Oberlin score was a point system with a maximal score of 4.6