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. 2020 Nov 5;21:272. doi: 10.1186/s13059-020-02183-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Condensin confines chromatin mobility in interphase. a MSD of chromatin mobility in wild type (WT), control (cut14⁺), and following condensin depletion (cut14^SO). Weighted mean (dotted line) and standard error (square boxes) are shown. Black dotted lines above and below mean MSD are the slopes corresponding to 0.6 and 0.5, respectively. b–d Histogram (gray bars) and kernel density estimate (colored circles) of probability density of individual MSD exponents in G2-arrested WT (b), cut14⁺ (c), and cut14^SO (d) cells. Solid lines are single Gaussian fit in case of WT and cut14⁺ and a double Gaussian fit for cut14^SO cells. The dotted lines show the two component Gaussians (n > 300)