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. Author manuscript; available in PMC: 2020 Nov 5.
Published in final edited form as: Annu Rev Microbiol. 2020 Sep 8;74:39–63. doi: 10.1146/annurev-micro-020518-115628

Figure 1.

Figure 1

Evolutionary relationships of primate and rodent Plasmodium species inferred from whole genome sequences. A maximum-likelihood tree of deduced protein sequences from 1,693 orthologous genes is shown. Two strains of P. praefalciparum are included to illustrate the position of P. falciparum within the radiation of this species. The G03 sequence was obtained by SNP calling of published reads using P. falciparum for reference (97). Human parasites are shown in red, with the zoonotic parasite P. knowlesi indicated by a red asterisk. The tree was rooted using the bird parasites P. gallinaceum and P. relictum as outgroups. Sequence data and gene annotations were derived from published genome assemblies (6, 12, 25, 58, 75, 96–98, 102–103, 120) and PlasmoDB. All relationships were supported by 100% of bootstrap replicates except for the position of P. cynomolgi. The scale bar indicates amino acid substitutions per site.