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. 2020 Nov 5;20:453. doi: 10.1186/s12877-020-01835-x

Table 4.

Univariate and multivariate analysis on the factors potentially associated with having at least one EDA or HA, by setting

Nursing Home (n = 646) Home Care (n = 1054)
PwD with at least one EDA or HA (n = 89; 13.8%) PwD without EDA or HA (n = 557; 86.2%) p_value Unadjusted OR [95%CI] Adjusted OR [95%CI] PwD with at least one EDA or HA (N = 195; 18.5%) PwD without EDA or HA (n = 859; 81.5%) p_value Unadjusted OR [95%CI] Adjusted OR [95%CI]
Age (years) n (%) 0.120 0.562
 65–80 years 17 (19.1%) 151 (27.1%) Reference Reference 65 (33.3%) 307 (35.7%) Reference Reference
  ≥ 81 years 72 (80.9%) 406 (72.9%) 1.58 (0.90–2.76) 1.94 (0.98–3.85) 130 (66.7%) 552 (64.3%) 1.11 (0.80–1.55) 1.12 (0.78–1.61)
Sex, n (%) 0.085 0.282
 Female 60 (67.4%) 426 (76.5%) Reference Reference 119 (61.0%) 560 (65.2%) Reference Reference
 Male 29 (32.6%) 131 (23.5%) 1.57 (0.97–2.55) 1.55 (0.88–2.75) 76 (39.0%) 299 (34.8%) 1.20 (0.87–1.65) 1.06 (0.74–1.52)
S-MMSE score, n (%),a 0,954 0,175
 Mild dementia 8 (12.5%) 58 (12.8%) Reference Reference 42 (24.6%) 198 (26.3%) Reference Reference
 Moderate dementia 37 (57.8%) 242 (53.3%) 1.11 (0.49–2.51) 1.00 (0.42–2.38) 81 (47.4%) 396 (52.6%) 0,96 (0,64-1,45) 0.93 (0.60–1.45)
 Severe dementia 19 (29.7%) 154 (33.9%) 0.89 (0.37–2.16) 1.13 (0.46–2.78) 48 (28.1%) 159 (21.1%) 1.42 (0.90–2.26) 1.3 (0.78–2.17)
Weight loss, n (%) 0.724 0.002
 No 80 (89.0%) 485 (86.6%) Reference Reference 140 (70.9%) 703 (81.4%) Reference Reference
 Yes 9 (11.0%) 72 (13.4%) 0.80 (0.38–1.67) 0.72 (0.32–1.62) 55 (29.1%) 156 (18.6%) 1.79 (1.25–2.57) 1.73 (1.17–2.56)
Polypharmacy, n (%) 0.049 < 0.001
 No 20 (22.5%) 186 (33.4%) Reference Reference 51 (26.2%) 399 (46.4%) Reference Reference
 Yes 69 (77.5%) 371 (66.6%) 1.73 (1.02–2.93) 1.96 (1.03–3.75) 144 (73.8%) 460 (53.6%) 2.45 (1.73–3.46) 2.48 (1.70–3.62)
Falls in preceding 3 months n (%) 0.009 0.001
 No 55 (61.4%) 419 (75.1%) Reference Reference 137 (70.1%) 702 (81.7%) Reference Reference
 Yes 34 (38.6%) 138 (24.9%) 1.90 (1.19–3.05) 1.66 (0.96–2.86) 58 (29.9%) 157 (18.3%) 1.91 (1.34–2.71) 1.64 (1.12–2.41)
Charlson Comorbidity Index n (%) 0.906 0.076
  ≤ 2 55 (61.8%) 349 (62.7%) Reference Reference 131 (67.2%) 632 (73.6%) Reference Reference
  > 2 34 (38.2%) 208 (37.3%) 1.04 (0.65–1,64) 1.04 (0.61–1.77) 64 (32.8%) 227 (26.4%) 1.36 (0.97–1.90) 1.13 (0.78–1.64)
Katz Index, n (%) 0.221 0.029
 Severe 60 (67.4%) 327 (58.9%) 2.94 (0.69–12.58) 2.00 (0.44–9.04) 84 (43.3%) 281 (33.1%) 1.60 (1.01–2.54) 1.24 (0.72–2.15)
 Moderate 27 (30.3%) 196 (35.3%) 2.20 (0.50–9.72) 1.96 (0.43–8.97) 80 (41.2%) 407 (47.9%) 1.06 (0.67–1.67) 0.95 (0.57–1.58)
 Mild 2 (2.2%) 32 (5.8%) Reference Reference 30 (15.5%) 161 (19.0%) Reference Reference
NPI-Q Severity, mean (SD) 7.7 (6.0) 6.8 (5.7) 0.174 1.03 (1.00–1.07) 1.02 (0.97–1.07) 9.9 (6.1) 9.0 (6.2) 0.069 1.02 (1.00–1.05) 0.99 (0.96–1.02)
Zarit Burden Index n (%) 0.511 0.018
 Little or no burden 47 (53.4%) 264 (47.6%) Reference Reference 37 (19.0%) 227 (26.5%) Reference Reference
 Mild burden 28 (31.8%) 211 (38.0%) 0.75 (0.45–1.23) 0.6 (0.34–1.1) 88 (45.1%) 398 (46,5%) 1.36 (0.89–2.06) 1.67 (1.04–2.66)
 Moderate to severe burden 13 (14.8%) 80 (14.4%) 0.91 (0.47–1.77) 1.00 (0.47–2.15) 70 (35.9%) 231 (27.0%) 1.86 (1.20–2.88) 1.76 (1.04–2.98)

CI Confidence Interval, EDA Emergency Department Admission, HA Hospital Admission, OR Odds Ratio, PwD People with Dementia

a Mild Dementia (S-MMSE score > 21), Moderate Dementia (S-MMSE score 10–21), or Severe Dementia (S-MMSE score < 10 or not evaluated due to impaired cognitive or functional status)