Table 1.

Summarize of G6PC2, GCK, GCKR, and OCT3 gene polymorphism with T2DM in various ethnic groups

Gene	Polymorphism	Significance	OR	Case/Control	Ethnicity	References
G6PC2	rs492594 G > C	Y	0.57	538/538	Han Chinese	[12]
	rs492594 G > C	Y	1.14	1876/1800	Eastern Han Chinese	[13]
	rs492594 G > C	Y	1.70	185/377	RIYADH COHORT	[14]
	rs13387347 T > C	Y	1.17	1876/1800	Eastern Han Chinese	[13]
	rs13387347 T > C	N		538/538	Han Chinese	[12]
	rs16856187 A > C	Y	1.19	1876/1800	Eastern Han Chinese	[13]
	rs16856187 A > C	N		538/538	Han Chinese	[12]
	rs2232316 G > A	N		1876/1800	Eastern Han Chinese	[13]
	rs2232328 C > G	Y	1.64	185/377	RIYADH COHORT	[14]
GCK	rs4607517 T > C	Y	1.20	853/3210	American Indians	[15]
	rs1476891 A > G	Y	1.26	1658/1946	Pima Indians	[15]
	rs55714218 G>-	Y	0.84	853/3210	American Indians	[15]
	rs1799884 G > A	Y	1.12	2628/2041	Netherlands	[16]
	rs1799884 G > A	Y	1.23	1244/3189	French	[17]
	rs1799884 G > A	Y	1.24	1193/1055	Moroccans	[18]
GCKR	rs780094 G > A	Y	1.78	538/538	Han Chinese	[12]
	rs780094 G > A	Y	0.67	424/1884	Han Chinese	[19]
	rs780094 G > A	N		736/768	Northern Han Chinese	[20]
	rs780094 G > A	Y	0.71	488/398	Japanese	[21]
	rs780094 G > A	Y	1.22	1118/1161	Han Chinese	[22]
	rs1260326 C > T	Y	0.74	424/1884	Han Chinese	[19]
	rs1260326 C > T	N		538/538	Han Chinese	[12]
	rs2293572 C > G	N		538/538	Han Chinese	[12]
	rs3817588 A > G	Y	1.24	1118/1161	Han Chinese	[22]
OCT3	rs3088442 G > A	Y	0.02	150/152	Iran	[23]
	rs2292334 G > A	Y	2.76	150/152	Iran	[23]