Table 2.

Location of first disease relapse at a distant site

	Group A (≤12 months) n=201 No. (%)	Group B (>12 months) n=203 No. (%)	P value
Type of metastatic presentation (distant relapse)*			0.195
Visceral	139 (69)	128 (63)
Non-visceral	62 (31)	75 (37)
Metastatic site (distant relapse)†			0.073
Brain	52 (26)	31 (15)
Liver	46 (23)	60 (30)
Lung	37 (18)	33 (16)
Bone	43 (21)	51 (25)
Others	23 (11)	28 (14)
Type of metastatic presentation (distant relapse)*			0.289
Visceral	139 (77)	128 (72)
Bone (without visceral)	42 (23)	50 (28)

*Patients with bone, skin, lymph node and soft tissue were considered as non-visceral; all the others were considered as visceral.

†For patients who developed relapse in more than one organ, the first site of distant metastasis was defined by prespecified importance in the following order: brain, liver, lung, bone and others. The category ‘others’ included: skin, lymph node, soft tissue, pleura and other rarer sites of relapse.