Table 3.
Incidence and Duration of Adverse Events
| Patients (n = 12) | |
|---|---|
| Numbness, n (%) | 12 (100) |
| Duration, all treatments, mean ± SD, days | 18.6 ± 5.7a |
| Duration among patients who received 1 treatment, mean ± SD, days | 25.5 ± 2.9 |
| Duration in first treatment, mean ± SD, days | 20.8 ± 5.7 |
| Duration among patients who received ≥2 treatments, mean ± SD, days | 16.8 ± 4.8 |
| Duration in subsequent treatments, mean ± SD, days | 15.8 ± 4.3 |
| Edema, n (%) | 12 (100) |
| Duration, all treatments, mean ± SD, days | 6.0 ± 3.3b |
| Duration among patients who received 1 treatment, mean ± SD, days | 9.3 ± 4.6 |
| Duration in first treatment, mean ± SD, days | 8.1 ± 3.2 |
| Duration among patients who received ≥2 treatments, mean ± SD, days | 5.2 ± 2.4 |
| Duration in subsequent treatments, mean ± SD, days | 3.6 ± 1.3 |
| Tenderness, n (%) | 11 (92) |
| Duration, all treatments, mean ± SD, days | 4.5 ± 2.4 |
| Duration among patients who received 1 treatment, mean ± SD, days | 6.7 ± 2.9 |
| Duration in first treatment, mean ± SD, days | 4.7 ± 2.9 |
| Duration among patients who received ≥2 treatments, mean ± SD, days | 4.1 ± 2.1 |
| Duration in subsequent treatments, mean ± SD, days | 3.7 ± 2.0 |
| Bruising, n (%) | 5 (42)c |
| Duration, all treatments, mean, days | 4.8 |
| Duration among patients who received 1 treatment, mean, days | 4.0 |
| Duration in first treatment, mean, days | 5.2 |
| Duration among patients who received ≥2 treatments, mean, days | 5.3 |
| Duration in subsequent treatments, mean, days | 3.0 |
| Induration, n (%) | 1 (8)d |
SD, standard deviation. aDuration was unknown in 1 patient who received 1 treatment; duration was 18 days after the first treatment and of unknown duration after the second treatment in 1 patient. bDuration was unknown in 1 patient who received 1 treatment. cIn 1 patient, bruising occurred on the left side only during the first treatment; in 1 patient, bruising occurred only after the third of 4 treatments. dOccurred in 1 patient and lasted for 7 and 9 days after the first and second treatments, respectively.