Table 3.

Univariate and multivariate analysis of factors affecting the survival in heart disease–related death NSCLC patients.

Parameters	Nonimmunotherapy				Immunotherapy
	Univariate HR/CI	P value	Multivariate HR/CI	P value	Univariate HR/CI	P value	Multivariate HR(95% CI)	P value
Age (20-69 vs. >70)	1.06(0.82-1.36)	0.6	0.76(0.58-1.00)	0.05	0.92(0.72-1.17)	0.5	1.00(0.77-1.29	0.9
Sex Male vs. Female	1.07(0.83-1.38)	0.5	0.87(0.57-1.22)	0.3	1.03(0.80-1.33)	0.7	0.88 (0.67-1.16	0.3
Marital Yes - Others	0.84(0.66-1.07)	0.1	1.06(0.81-1.38)	0.6	0.93(0.73-1.18)	0.5	0.96(0.75-1.26)	0.8
Race
White	Reference		Reference		Reference		Reference
Black	0.81(0.57-1.15)	0.2	0.83(0.57-1.22)	0.3	0.97(0.70-1.34)	0.8	0.85(0.60-1.19)	0.3
Others	0.56(0.32-0.98)	0.04	0.51(0.28-0.91)	0.02	0.99(0.63-1.55)	0.9	0.82(0.51-1.30)	0.4
Chemotherapy yes vs. no	0.57(45-74)	<0.0001	1.72(1.31-2.25)	0.0001	1.76(1.38-2.26)	0.0001	1.81(1.37-2.38)	0.0001
Radiotherapy yes vs. no	0.61(48-0.79)	0.0001	1.47(1.12-1.93	0.005	1.46(1.13-1.87	0.003	1.29(0.98-1.70)	0.06
Grade
I-II	Reference		Reference				Reference
III-IV	1.14(0.80-1.62)	0.4	1.28(0.89-1.84	0.1	1.20(0.84-1.71)	0.3	1.24(0.86-1.79)	0.2
Unknown	1.30(0.95-1.77		1.23(0.88-1.72)	0.2	1.04(0.74-1.46)	0.8	1.05(0.73-1.49)	0.7
Laterality Left vs. Right	0.99(0.77-1.26)	0.9	1.02(0.79-1.32)	0.8	0.93(0.73-1.18)	0.5	1.21(0.93-1.57)	0.1
Histology/Behav
Adenocarcinoma	Reference						Reference
Squamous	0.77(0.57-1.04)	0.094	0.78(0.56-108)	0.1	0.80 (0.61-1.06)	0.133	0.74(0.55-0.99)	0.04
Others	0.71(0.053-0.09)	0.022	0.70(0.52-0.95)	0.02	1.12 (0.82-1.52)	0.474	0.96 (0.69-1.35)	0.8
Insurance yes vs. others	0.85(0.66-1.10)	0.228	1.07(0.81-1.41	0,6	1.21 (0.95-1.55)	0.114	1.25(0.96-1.61)	0.08