Table 2. Differences in ALFF between ALS and HC groups.
| Clusters | Brain regions | Cluster size (voxels) | MNI (X, Y, Z) | T value |
|---|---|---|---|---|
| ALS >HC | ||||
| Cluster 1 | Right inferior temporal gyrus | 128 | 45, −6, −45 | 4.14 |
| Cluster 2 | Left superior orbitofrontal gyrus | 442 | −15, 18, −15 | 4.45 |
| Cluster 3 | Right medial superior frontal gyrus | 93 | 6, 54, 27 | 4.35 |
| ALS <HC | ||||
| Cluster 1 | Left middle occipital gyrus | 895 | −27, 90, −3 | −4.56 |
| Cluster 2 | Left precentral gyrus | 108 | −27, −21, 72 | −3.81 |
Notes.
MNI, Montreal Neurological Institute. X, Y, Z, coordinates of primary peak locations in the MNI space.
- ALS
- Amyotrophic Lateral Sclerosis
- HC
- Healthy Control
T value denotes the statistic value of two-sample t-test by contrasting the ALS patients to the controls (p < 0.01, GRF-corrected at a cluster level of p < 0.05).