Table 3. Differences in d-ALFF between ALS and HC groups.
| Clusters | Brain regions | Cluster size (voxels) | MNI (X, Y, Z) | T value |
|---|---|---|---|---|
| ALS >HC | ||||
| None | ||||
| ALS <HC | ||||
| Cluster 1 | Right lingual gyrus | 988 | 24,−45, −9 | −4.35 |
| Cluster 2 | Left superior temporal gyrus | 176 | −48,−27, 12 | −3.82 |
| Cluster 3 | Bilateral precentral gyrus | 90 | 51,−9, 24 | −3.45 |
| Cluster 4 | Left paracentral lobule | 125 | −6, −15, 75 | −3.70 |
Notes.
MNI, Montreal Neurological Institute. X, Y, Z, coordinates of primary peak locations in the MNI space.
- ALS
- Amyotrophic Lateral Sclerosis
- HC
- Healthy Control
T value denotes the statistic value of two-sample t-test by contrasting the ALS patients to the controls (p < 0.01, GRF-corrected at a cluster level of p < 0.05).