Table 1.
The ACE2 correlated immune cell markers of toll-like receptors, macrophages, dendritic cells, natural killer cells, neutrophils, monocytes and cytokines in Luminal A subtype of breast cancer.
| Cell Type | Gene markers | COR | P-values |
|---|---|---|---|
| Toll-like receptors | TLR4 | 0.264 | 1.69E-10 |
| TLR7 | 0.104 | 1.34E-02 | |
| TLR8 | 0.25 | 1.57E-09 | |
| TLR9 | 0.35 | 9.04E-18 | |
| Macrophage | MS4A4A | 0.204 | 9.85E-07 |
| CD68 | 0.084 | 4.45E-02 | |
| CD163 | 0.158 | 1.54E-04 | |
| Dendritic Cells (DCs) | ITGAX | 0.145 | 5.08E-04 |
| FSCN1 | 0.176 | 2.59E-05 | |
| ADAM19 | 0.178 | 2.03E-05 | |
| Natural Killer cells (NK) | NCR1 | 0.198 | 1.92E-06 |
| NCAM1 | 0.344 | 3.44E-17 | |
| KLRB1 | 0.324 | 2.63E-15 | |
| Neutrophils | CEACAM3 | 0.178 | 1.96E-05 |
| FCGR3B | 0.115 | 6.01E-03 | |
| FPR1 | 0.136 | 1.21E-03 | |
| Monocyte | CSF1R | 0.15 | 3.44E-04 |
| CD86 | 0.121 | 3.77E-03 | |
| C3AR1 | 0.084 | 4.59E-02 | |
| Cytokines | IL2 | 0.203 | 1.03E-06 |
| IL1A | 0.068 | 0.101 | |
| IL10 | 0.200 | 1.47E-06 | |
| IL19 | 0.0350 | 0.403 | |
| IL20 | 0.006 | 0.868 | |
| IL21 | 0.149 | 0.0003 | |
| TNF | 0.057 | 0.173 | |
| CXCR2 | 0.166 | 6.45E-05 | |
| CSF1 | 0.075 | 0.071 | |
| CD274 | 0.251 | 1.21E-09 | |
| CTLA4 | 0.075 | 0.071 | |
| PDCD1 | 0.250 | 1.45E-09 |