Table 2.
The ACE2 correlated immune cell markers of toll-like receptors, macrophages, dendritic cells, natural killer cells, neutrophils, monocytes and cytokines in Basal-like subtype of breast cancer.
| Cell Type | Gene markers | COR | P-Values |
|---|---|---|---|
| Toll-like receptors | TLR4 | 0.126 | 0.081 |
| TLR7 | 0.198 | 0.005 | |
| TLR8 | 0.140 | 0.053 | |
| TLR9 | 0.135 | 0.060 | |
| Macrophage | MS4A4A | 0.201 | 0.005 |
| CD68 | 0.070 | 0.335 | |
| CD163 | 0.156 | 0.030 | |
| Dendritic Cells (DCs) | ITGAX | 0.072 | 0.320 |
| FSCN1 | −0.156 | 0.030 | |
| ADAM19 | 0.127 | 0.078 | |
| Natural Killer cells (NK) | NCR1 | 0.184 | 0.010 |
| NCAM1 | −0.096 | 0.183 | |
| KLRB1 | 0.108 | 0.136 | |
| Neutrophils | CEACAM3 | 0.033 | 0.64 |
| FCGR3B | 0.137 | 0.056 | |
| FPR1 | 0.105 | 0.145 | |
| Monocyte | CSF1R | 0.095 | 0.186 |
| CD86 | 0.167 | 0.020 | |
| C3AR1 | 0.161 | 0.025 | |
| Cytokines | IL2 | 0.083 | 0.249 |
| IL1A | 0.182 | 0.011 | |
| IL10 | 0.159 | 0.027 | |
| IL19 | 0.224 | 0.001 | |
| IL20 | 0.196 | 0.006 | |
| IL21 | 0.169 | 0.018 | |
| TNF | 0.139 | 0.053 | |
| CXCR2 | 0.302 | 2.14E-05 | |
| CSF1 | 0.166 | 0.021 | |
| CD274 | 0.260 | 0.0002 | |
| CTLA4 | 0.171 | 0.017 | |
| PDCD1 | 0.169 | 0.019 |