Table 4.
The ACE2 correlated immune cell markers of toll-like receptors, macrophages, dendritic cells, natural killer cells, neutrophils, monocytes and cytokines in Luminal B subtype of BC.
| Cell Type | Gene markers | COR | P-values |
|---|---|---|---|
| Toll-like receptors | TLR4 | 0.103 | 0.127 |
| TLR7 | 0.045 | 0.506 | |
| TLR8 | 0.107 | 0.113 | |
| TLR9 | 0.042 | 0.530 | |
| Macrophage | MS4A4A | 0.056 | 0.407 |
| CD68 | 0.038 | 0.566 | |
| CD163 | 0.056 | 0.407 | |
| Dendritic Cells (DCs) | ITGAX | 0.016 | 0.807 |
| FSCN1 | 0.001 | 0.987 | |
| ADAM19 | 0.181 | 0.007 | |
| Natural Killer cells (NK) | NCR1 | 0.154 | 0.223 |
| NCAM1 | 0.188 | 0.005 | |
| KLRB1 | 0.140 | 0.037 | |
| Neutrophils | CEACAM3 | 0.095 | 0.160 |
| FCGR3B | 0.035 | 0.598 | |
| FPR1 | 0.057 | 0.393 | |
| Monocyte | CSF1R | −0.022 | 0.742 |
| CD86 | 0.095 | 0.157 | |
| C3AR1 | 0.067 | 0.318 | |
| Cytokines | IL2 | 0.108 | 0.108 |
| IL1A | 0.127 | 0.058 | |
| IL10 | 0.139 | 0.039 | |
| IL19 | 0.077 | 0.252 | |
| IL20 | −0.035 | 0.603 | |
| IL21 | 0.187 | 0.005 | |
| TNF | 0.033 | 0.619 | |
| CXCR2 | 0.078 | 0.249 | |
| CSF1 | 0.009 | 0.884 | |
| CD274 | 0.250 | 0.0001 | |
| CTLA4 | 0.206 | 0.071 | |
| PDCD1 | 0.133 | 0.048 |