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Adapted from The Institute of Basic Science, depicting entry of the SARS-CoV-2 virus via the Spike protein and subsequent uncoating, transcription and RNA replication. The SARS-CoV-2 genome is translated forming the non-structural proteins responsible for the replicase-transcriptase. The positive sense strand of gRNA is translated to form the four structural proteins and the resulting nucleocapsid. Finally, the viral particle is packaged and trafficked to the membrane [8].
