Table 4.
Outcomes after treatment with curative‐intent radiation therapy (treated for first primary cancer)
|
Non‐RT n = 24 |
RT n = 9 |
P‐value | |
|---|---|---|---|
| Subsequent malignancy (# of pts) | |||
| Recurrent disease (same histology) | |||
| Local | 1 | 3 | |
| Distant/Metastasis | 0 | 0 | |
| New primary (different histology) | |||
| Local | 0 | 0 | |
| Distant | 10 | 2 | |
| Total | 11 (45.8%) | 5 (55.5%) | .7080 |
| Time to subsequent malignancy (months) | |||
| Mean | 103.6 (8.6y) | 42.6 (3.5y) | |
| Median | 60 (5.0y) | 39 (3.3) | |
| Range | 11‐329 | 17‐90 | |
| Number of deaths to date | 1 | 5 | <.001 |
| Time to death from first primary (months) | |||
| Mean | 347 (28.9y) | 47.4 (3.9y) | |
| Median | 347 (28.9y) | 54 (4.5y) | |
| Range | na | 8‐57 | |
| Prognosis at diagnosis | |||
| Pre‐invasive | 4 (16.7%) | 0 (0.0%) | |
| Favorable | 17 (70.8%) | 3 (33.3%) | |
| Unfavorable | 3 (12.5%) | 6 (66.7%) | .01 |
| 10‐year overall survival | 100% | 44.4% | <.001 |
Bold values indicates P ‐values < .05.
Abbreviations: pts, patients; RT, radiation therapy; y, years.