Table 3.

Chronic Pain Management Platform: Symptom and Co-Morbidity Instruments

Symptom or Comorbidity	Comorbidities and Symptoms	Score
Fatigue	Fatigue Severity Scale 48,49	Single score as average of 9 items; presence of fatigue ≥ 4. Note: mean 2.3 (SD +/- 0.7 in normal healthy adults)
Depression	PHQ-9 Depression Scale 50	Score range 0 – 27 Minimal Depression (score 0 – 4) Mild Depression (score 5 – 9) Moderate Depression (score 10 – 14) Moderately severe depression (score 15 – 19) Severe Depression (score 20+)
Anxiety	GAD-7 Anxiety Scale 51	Score range 0-28 None or very mild anxiety (score 0 – 4) Mild anxiety (score 5 – 9) Moderate anxiety (10-15) Severe anxiety (16+)
Constipation	PAC-SYM Questionnaire 52	Score averaged over 11 items (range 0 – 4) Average or mild constipation (score 0 – 0.9) Moderate constipation (score 1.0 – 2.9 Severe or very severe constipation (Score 3.0+)
Sleep	RAND Sleep Report and Questionnaire 53	Sleep Experience (last 2 weeks): Time taken to fall asleep, hours of sleep. RAND Sleep (score 0 – 50; 0 = no problems to 50 extreme problems)