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Evaluation of Probability of Target Attainment for Different Rifampicin Doses
| Rifampicin Dose, mg | Approximate Dose/Body Weight, mg/kg | Probability of Plasma AUC0-24h at Day 2 ± 1 > 171 mg/L × h, % | Probability of Plasma AUC0-24h at Day 2 ± 1 > 300 mg/L × h, % |
|---|---|---|---|
| 450 | 10 | 0.47 | 0 |
| 900 | 20 | 67.8 | 11.4 |
| 1350 | 30 | 97.6 | 70.1 |
| 1800 | 40 | 99.8 | 94.5 |
Abbreviation: AUC0-24h, area under the rifampicin plasma concentration curve from 0 to 24 hours after dose.
