Figure 4.
Change from baseline in homeostasis model assessment–insulin resistance (HOMA-IR) in the safety population. Geometric mean ratio and 95% confidence interval for postbaseline values based on a loge transformation. Change from baseline was calculated using a repeated measures model adjusting for treatment, visit, baseline third agent class, CD4+ cell count (continuous), age (continuous), sex, race, body mass index (continuous), presence of hypertension, loge-transformed baseline HOMA-IR, treatment-by-visit interaction, and baseline value-by-visit interaction, with visit as the repeated factor. Abbreviations: 3TC, lamivudine; CI, confidence interval; DTG, dolutegravir; TAF, tenofovir alafenamide.