FIG. 2.

Evolutionary relationships among CCHFVs based on the small (S) segment. This tree and the M and L trees in Figure 4 were generated using maximum likelihood methods (RAxML-HPC BlackBox v8.2.10) implemented in CIPRES Science Gateway. CCHFV strain Cáceres 2014 from Spain is shown in bold. Scale bar indicates nucleotide substitution per site. An asterisk at a node indicates >90% bootstrap support, based on 1000 replicates. The different CCHFV clades are labeled with Roman numerals I–VI, designation by Bente et al. (2013). Branch labels are GenBank accession numbers.