Table 1.

Take-Home Messages.

Criterion	Hematologic Finding
Peripheral Blood Cells	Lymphopenia and thrombocytopenia/thrombocytosis Reduced lymphocytes with Increased neutrophils is associated with higher mortality rates
Inflammatory Markers	“Cytokine storm”: markedly increased serum levels of IL-2, IL-6, IL-7, granulocyte colony-stimulating factor, and TNF-alpha Contribute to apoptosis and lymphoid system atrophy
Endothelial Lung Dysfunction	Increased vWF, Increased thrombomodulin Reduced level of ADAMS 13
Coagulopathy	High levels of D-Dimers associated with greater mortality among patients with sepsis Association with a high level of pro-inflammatory cytokines
Viral Load	RNAaemia can be considered as a prognostic predictor for cytokine storm and severe or critically ill patients A significant positive correlation between the SARS-CoV-2 RNA load and IL-2R
Systemic Iron	Regulates hepcidin production and enhances iron sequestration in macrophages Hyperferritinemia not a common feature of COVID-19, unlike patients with typical HLH